Browsing San Diego Zoo Wildlife Alliance Research by Author "Eichler, E. E."

Now showing items 1-2 of 2

    • Copy number variation analysis in the great apes reveals species-specific patterns of structural variation
      Gazave, E.; Darre, F.; Morcillo-Suarez, C.; Petit-Marty, N.; Carreno, A.; Marigorta, U. M.; Ryder, Oliver A.; Blancher, A.; Rocchi, M.; Bosch, E.; et al. (2011)
      ...We performed intraspecific comparative genomic hybridizations to identify loci harboring copy number variants in each of the four great apes: bonobos, chimpanzees, gorillas, and orangutans. For the first time, we could analyze differences in CNV location and frequency in these four species, and compare them with human CNVs and primate segmental duplication (SD) maps....

    • Genome-wide characterization of centromeric satellites from multiple mammalian genomes
      Alkan, C.; Cardone, M. F.; Catacchio, C. R.; Antonacci, F.; O'Brien, S. J.; Ryder, Oliver A.; Purgato, S.; Zoli, M.; Della Valle, G.; Eichler, E. E.; et al. (2011)
      ...We analyzed genome datasets from six species of mammals representing the diversity of the mammalian lineage, namely, horse, dog, elephant, armadillo, opossum, and platypus. We define candidate monomer satellite repeats and demonstrate centromeric localization for five of the six genomes....