• Systemic amyloid A amyloidosis in island foxes (Urocyon littoralis): Severity and risk factors

      Gaffney, Patricia M.; Witte, Carmel L.; Clifford, D. L.; Imai, D. M.; O’Brien, T. D.; Trejo, M.; Liberta, F.; Annamalai, K.; Fändrich, M.; Masliah, E.; et al. (2016)
      ...Here we define the severity of glomerular and medullary renal amyloid and identify risk factors for AA amyloidosis in 321 island foxes necropsied from 1987 through 2010. In affected kidneys, amyloid more commonly accumulated in the medullary interstitium than in the glomeruli (98% [n = 78 of 80] vs 56% [n = 45], respectively; P < .0001), and medullary deposition was more commonly severe (19% [n = 20 of 105]) as compared with glomeruli (7% [n = 7]; P = .01)....
    • Systemic amyloidosis in an African tiger snake (Telescopus semiannulatus)

      Burns, Rachel E.; Gaffney, Patricia M.; Nilsson, K. P. R.; Armién, A. G.; Pessier, Allan P. (2017)
      Summary An adult male African tiger snake (Telescopus semiannulatus) was diagnosed with disseminated mycobacteriosis and a hepatic biliary cystadenocarcinoma. Histologically, the spleen was largely replaced by extracellular deposits of eosinophilic, fibrillar to hyaline material....