• Density trends and demographic signals uncover the long-term impact of transmissible cancer in Tasmanian devils

      Lazenby, Billie T.; Tobler, Mathias W.; Brown, William E.; Hawkins, Clare E.; Hocking, Greg J.; Hume, Fiona; Huxtable, Stewart J.; Iles, Philip; Jones, Menna E.; Lawrence, Clare; et al. (2018)
      Monitoring the response of wild mammal populations to threatening processes is fundamental to effective conservation management. This is especially true for infectious diseases, which may have dynamic and therefore unpredictable interactions with their host....
    • TP53 gene and cancer resistance in elephants

      Pessier, Allan P.; Stern, Jere K.; Witte, Carmel L. (2016)
      To the Editor: The study by Dr Abegglen and colleagues affirmed the Peto paradox and suggested that elephants are cancer resistant by virtue of multiple TP53 gene copies and enhanced responses to DNA damage. This study epitomizes a “One Health” approach to solving important disease problems shared by humans and animals. However, from our experience working in a large zoo-based , we were surprised by the results because, unlike in the notoriously cancer-resistant naked mole rats, we have diagnosed cancers in several elephants.