Extreme selective sweeps independently targeted the X chromosomes of the great apes

Nam, Kiwoong; Munch, Kasper; Hobolth, Asger; Dutheil, Julien Yann; Veeramah, Krishna R.; Woerner, August E.; Hammer, Michael F.; Great Ape Genome Diversity  Project; Mailund, Thomas; Schierup, Mikkel Heide; Prado-Martinez, Javier; Sudmant, Peter H.; Kidd, Jeffrey M.; Li, Heng; Kelley, Joanna L.; Lorente-Galdos, Belen; Veeramah, Krishna R.; Woerner, August E.; O’Connor, Timothy D.; Santpere, Gabriel; Cagan, Alexander; Theunert, Christoph; Casals, Ferran; Laayouni, Hafid; Munch, Kasper; Hobolth, Asger; Halager, Anders E.; Malig, Maika; Hernandez-Rodriguez, Jessica; Hernando-Herraez, Irene; Prüfer, Kay; Pybus, Marc; Johnstone, Laurel; Lachmann, Michael; Alkan, Can; Twigg, Dorina; Petit, Natalia; Baker, Carl; Hormozdiari, Fereydoun; Fernandez-Callejo, Marcos; Dabad, Marc; Wilson, Michael L.; Stevison, Laurie S.; Camprubí, Cristina; Carvalho, Tiago; Ruiz-Herrera, Aurora; Vives, Laura; Mele, Marta; Abello, Teresa; Kondova, Ivanela; Bontrop, Ronald E.; Pusey, Anne; Lankester, Felix; Kiyang, John A.; Bergl, Richard A.; Lonsdorf, Elizabeth; Myers, Simon; Ventura, Mario; Gagneux, Pascal; Comas, David; Siegismund, Hans; Blanc, Julie; Agueda-Calpena, Lidia; Gut, Marta; Fulton, Lucinda; Tishkoff, Sarah A.; Mullikin, James C.; Wilson, Richard K.; Gut, Ivo G.; Gonder, Mary Katherine; Ryder, Oliver A.; Hahn, Beatrice H.; Navarro, Arcadi; Akey, Joshua M.; Bertranpetit, Jaume; Reich, David; Mailund, Thomas; Schierup, Mikkel Heide; Hvilsom, Christina; Andrés, Aida M.; Wall, Jeffrey D.; Bustamante, Carlos D.; Hammer, Michael F.; Eichler, Evan E.; Marques-Bonet, Tomas

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Issue Date

2015

Author

Nam, Kiwoong
Munch, Kasper
Hobolth, Asger
Dutheil, Julien Yann
Veeramah, Krishna R.
Woerner, August E.
Hammer, Michael F.
Great Ape Genome Diversity Project
Mailund, Thomas
Schierup, Mikkel Heide

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Subject

APES
EVOLUTION
CHROMOSOMES
GENOMICS

Journal title

Proceedings of the National Academy of Sciences

Volume

112

Issue

Begin page

6413

End page

6418

Abstract

…We perform a comparative analysis of X chromosome polymorphism in 10 great ape species, including humans. In most species, we identify striking megabase-wide regions, where nucleotide diversity is less than 20% of the chromosomal average....

URI

http://hdl.handle.net/20.500.12634/410

Type

Article

Rights

PNAS Open Access Option

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ICR Research Publications

Extreme selective sweeps independently targeted the X chromosomes of the great apes

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Extreme selective sweeps independently targeted the X chromosomes of the great apes

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End page

Metadata

DOI

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Abstract

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