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    Generation of induced pluripotent stem cells from mammalian endangered species

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    Issue Date
    2015
    Author
    Ben-Nun, Inbar Friedrich
    Montague, Susanne C.
    Houck, Marlys L.
    Ryder, Oliver A.
    Loring, Jeanne F.
    Editor
    Verma P.
    Sumer H.
    Subject
    EXPERIMENTAL METHODS
    MAMMALS
    ENDANGERED SPECIES
    TECHNOLOGICAL INNOVATIONS
    WILDLIFE CONSERVATION
    Book title
    Cell Reprogramming
    Series
    Methods in Molecular Biology
    Volume
    1330
    Begin page
    101
    End page
    109
    
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    DOI
    10.1007/978-1-4939-2848-4_10
    Alternative link
    https://link.springer.com/protocol/10.1007/978-1-4939-2848-4_10
    Abstract
    For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent their extinction. Cellular reprogramming is a means to capture the genomes of individual animals as induced pluripotent stem cells (iPSCs), which may eventually facilitate reintroduction of genetic material into breeding populations. Here, we describe a method for generating iPSCs from fibroblasts of mammalian endangered species.
    URI
    http://hdl.handle.net/20.500.12634/423
    Type
    Book Chapter
    Rights
    © Springer Science+Business Media New York 2015
    ae974a485f413a2113503eed53cd6c53
    10.1007/978-1-4939-2848-4_10
    Scopus Count
    Collections
    Conservation Science Publications

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