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    Orangutan Alu quiescence reveals possible source element: support for ancient backseat drivers

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    Issue Date
    2012
    Author
    Walker, Jerilyn A.
    Konkel, Miriam K.
    Ullmer, Brygg
    Monceaux, Christopher P.
    Ryder, Oliver A.
    Hubley, Robert
    Smit, Arian FA
    Batzer, Mark A.
    Subject
    ORANGUTANS
    PRIMATES
    GENOMICS
    CHROMOSOMES
    EXPERIMENTAL METHODS
    EVOLUTION
    Journal title
    Mobile DNA
    Volume
    3
    Issue
    1
    Begin page
    8
    
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    DOI
    10.1186/1759-8753-3-8
    Abstract
    Sequence analysis of the orangutan genome revealed that recent proliferative activity of Alu elements has been uncharacteristically quiescent in the Pongo (orangutan) lineage, compared with all previously studied primate genomes. With relatively few young polymorphic insertions, the genomic landscape of the orangutan seemed like the ideal place to search for a driver, or source element, of Alu retrotransposition.
    URI
    http://hdl.handle.net/20.500.12634/713
    Type
    Article
    Rights
    Copyright © 2012, Springer Nature
    ae974a485f413a2113503eed53cd6c53
    10.1186/1759-8753-3-8
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