Human and great ape red blood cells differ in plasmalogen levels and composition
dc.contributor.author | Moser, A.B. | |
dc.contributor.author | Steinberg, S.J. | |
dc.contributor.author | Watkins, P.A. | |
dc.contributor.author | Moser, H.W. | |
dc.contributor.author | Ramaswamy, K. | |
dc.contributor.author | Siegmund, K.D. | |
dc.contributor.author | Lee, D.R. | |
dc.contributor.author | Ely, J.J. | |
dc.contributor.author | Ryder, Oliver A. | |
dc.contributor.author | Hacia, J.G. | |
dc.date.accessioned | 2021-02-02T01:45:33Z | |
dc.date.available | 2021-02-02T01:45:33Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 1476-511X | |
dc.identifier.doi | 10.1186/1476-511X-10-101 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12634/827 | |
dc.description.abstract | Plasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease. | |
dc.description.sponsorship | ||
dc.language.iso | en | |
dc.relation.url | https://doi.org/10.1186/1476-511X-10-101 | |
dc.rights | © 2011 Moser et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
dc.rights.uri | http://creativecommons.org/licenses/by/2.0 | |
dc.subject | MICROBIOLOGY | |
dc.subject | DEVELOPMENT | |
dc.subject | PHYSIOLOGY | |
dc.subject | MAMMALOGY | |
dc.subject | IMMUNOLOGY | |
dc.subject | NEUROLOGY | |
dc.subject | BIOCHEMISTRY | |
dc.subject | RESEARCH | |
dc.subject | NERVOUS SYSTEM | |
dc.subject | CARDIOVASCULAR SYSTEM | |
dc.subject | PATHOLOGY | |
dc.subject | APES | |
dc.subject | HUMANS | |
dc.title | Human and great ape red blood cells differ in plasmalogen levels and composition | |
dc.type | Article | |
dc.source.journaltitle | Lipids in Health and Disease | |
dc.source.volume | 10 | |
dc.source.issue | 1 | |
dc.source.beginpage | 101 | |
refterms.dateFOA | 2021-02-02T02:16:17Z | |
html.description.abstract | Plasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease. |
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Peer reviewed and scientific works by San Diego Zoo Wildlife Alliance staff. Includes books, book sections, articles and conference publications and presentations.