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dc.contributor.authorMoser, A.B.
dc.contributor.authorSteinberg, S.J.
dc.contributor.authorWatkins, P.A.
dc.contributor.authorMoser, H.W.
dc.contributor.authorRamaswamy, K.
dc.contributor.authorSiegmund, K.D.
dc.contributor.authorLee, D.R.
dc.contributor.authorEly, J.J.
dc.contributor.authorRyder, Oliver A.
dc.contributor.authorHacia, J.G.
dc.date.accessioned2021-02-02T01:45:33Z
dc.date.available2021-02-02T01:45:33Z
dc.date.issued2011
dc.identifier.issn1476-511X
dc.identifier.doi10.1186/1476-511X-10-101
dc.identifier.urihttp://hdl.handle.net/20.500.12634/827
dc.description.abstractPlasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease.
dc.description.sponsorship
dc.language.isoen
dc.relation.urlhttps://doi.org/10.1186/1476-511X-10-101
dc.rights© 2011 Moser et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.subjectMICROBIOLOGY
dc.subjectDEVELOPMENT
dc.subjectPHYSIOLOGY
dc.subjectMAMMALOGY
dc.subjectIMMUNOLOGY
dc.subjectNEUROLOGY
dc.subjectBIOCHEMISTRY
dc.subjectRESEARCH
dc.subjectNERVOUS SYSTEM
dc.subjectCARDIOVASCULAR SYSTEM
dc.subjectPATHOLOGY
dc.subjectAPES
dc.subjectHUMANS
dc.titleHuman and great ape red blood cells differ in plasmalogen levels and composition
dc.typeArticle
dc.source.journaltitleLipids in Health and Disease
dc.source.volume10
dc.source.issue1
dc.source.beginpage101
refterms.dateFOA2021-02-02T02:16:17Z
html.description.abstractPlasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease.


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© 2011 Moser et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as © 2011 Moser et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.