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    Induced pluripotent stem cells from highly endangered species

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    Issue Date
    2011
    Author
    Ben-Nun, Inbar Friedrich
    Montague, Susanne C
    Houck, Marlys L.
    Tran, Ha T
    Garitaonandia, Ibon
    Leonardo, Trevor R
    Wang, Yu-Chieh
    Charter, Suellen J.
    Laurent, Louise C
    Ryder, Oliver A.
    Loring, Jeanne F
    Show allShow less
    Subject
    BIODIVERSITY
    GENOMICS
    ENDANGERED SPECIES
    REPRODUCTION
    STEM CELLS
    MANDRILLS
    WHITE RHINOCEROSES
    BREEDING
    Journal title
    Nature Methods
    Volume
    8
    Issue
    10
    Begin page
    829
    End page
    831
    
    Metadata
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    DOI
    10.1038/nmeth.1706
    Alternative link
    http://www.nature.com/articles/nmeth.1706
    Abstract
    For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. We report generation of induced pluripotent stem cells (iPSCs) from two endangered species: a primate, the drill, Mandrillus leucophaeus and the nearly extinct northern white rhinoceros, Ceratotherium simum cottoni. iPSCs may eventually facilitate reintroduction of genetic material into breeding populations.
    URI
    http://hdl.handle.net/20.500.12634/843
    Type
    Article
    Rights
    Copyright © 2011, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
    ae974a485f413a2113503eed53cd6c53
    10.1038/nmeth.1706
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