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Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination: The comparative biology of mammalian telomeres

dc.contributor.authorGomes, Nuno M. V.
dc.contributor.authorRyder, Oliver A.
dc.contributor.authorHouck, Marlys L.
dc.contributor.authorCharter, Suellen J.
dc.contributor.authorWalker, William
dc.contributor.authorForsyth, Nicholas R.
dc.contributor.authorAustad, Steven N.
dc.contributor.authorVenditti, Chris
dc.contributor.authorPagel, Mark
dc.contributor.authorShay, Jerry W.
dc.contributor.authorWright, Woodring E.
dc.date.accessioned2021-02-10T00:30:42Z
dc.date.available2021-02-10T00:30:42Z
dc.date.issued2011
dc.identifier.issn14749718
dc.identifier.doi10.1111/j.1474-9726.2011.00718.x
dc.identifier.urihttp://hdl.handle.net/20.500.12634/857
dc.description.abstract...We examined telomeres/telomerase in cultured cells from >?60 mammalian species to place different uses of telomeres in a broad mammalian context. Phylogeny?based statistical analysis reconstructed ancestral states. Our analysis suggested that the ancestral mammalian phenotype included short telomeres (
dc.description.sponsorship
dc.language.isoen
dc.relation.urlhttp://doi.wiley.com/10.1111/j.1474-9726.2011.00718.x
dc.rights© 2011 The Authors. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
dc.subjectMAMMALS
dc.subjectCHROMOSOMES
dc.subjectLONGEVITY
dc.subjectRESEARCH
dc.subjectTAXONOMIES
dc.titleComparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination: The comparative biology of mammalian telomeres
dc.typeArticle
dc.source.journaltitleAging Cell
dc.source.volume10
dc.source.issue5
dc.source.beginpage761
dc.source.endpage768
html.description.abstract...We examined telomeres/telomerase in cultured cells from >?60 mammalian species to place different uses of telomeres in a broad mammalian context. Phylogeny?based statistical analysis reconstructed ancestral states. Our analysis suggested that the ancestral mammalian phenotype included short telomeres (<?20?kb, as we now see in humans) and repressed telomerase.....


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    Peer reviewed and scientific works by San Diego Zoo Wildlife Alliance staff. Includes books, book sections, articles and conference publications and presentations.

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