Show simple item record

dc.contributor.authorRuggeri, Elena
dc.contributor.authorLira-Albarrán, Saúl
dc.contributor.authorGrow, Edward J
dc.contributor.authorLiu, Xiaowei
dc.contributor.authorHarner, Royce
dc.contributor.authorMaltepe, Emin
dc.contributor.authorRamalho-Santos, Miguel
dc.contributor.authorDonjacour, Annemarie
dc.contributor.authorRinaudo, Paolo
dc.date.accessioned2021-03-19T17:31:21Z
dc.date.available2021-03-19T17:31:21Z
dc.date.issued2020
dc.identifier.issn1460-2407
dc.identifier.doi10.1093/molehr/gaaa064
dc.identifier.urihttp://hdl.handle.net/20.500.12634/955
dc.description.abstract…Animal studies indicate that IVF offspring display metabolic alterations, including hypertension, glucose intolerance and cardiac hypertrophy, often in a sexual dimorphic fashion. The detailed nature of epigenetic changes following in-vitro culture is, however, unknown. This study was performed to evaluate the epigenetic (using whole-genome bisulfite sequencing (WGBS) and assay for transposase-accessible chromatin using sequencing (ATAC-seq)) and transcriptomic changes (using RNA-seq) occurring in the inner cell mass (ICM) of male or female mouse embryos generated in vivo or by IVF....
dc.language.isoen
dc.relation.urlhttps://doi.org/10.1093/molehr/gaaa064
dc.rightsCopyright © 2020, Oxford University Press
dc.subjectREPRODUCTION
dc.subjectMETABOLISM
dc.subjectSEX DIFFERENCES
dc.subjectFERTILIZATION
dc.subjectGENOMICS
dc.subjectDEVELOPMENT
dc.subjectEXPERIMENTAL METHODS
dc.subjectEMBRYOLOGY
dc.subjectNEW WORLD MICE
dc.subjectARTIFICIAL INSEMINATION
dc.titleSex-specific epigenetic profile of inner cell mass of mice conceived in vivo or by IVF
dc.typeArticle
dc.source.journaltitleMolecular Human Reproduction
dc.source.volume26
dc.source.issue11
dc.source.beginpage866
dc.source.endpage878
html.description.abstract…Animal studies indicate that IVF offspring display metabolic alterations, including hypertension, glucose intolerance and cardiac hypertrophy, often in a sexual dimorphic fashion. The detailed nature of epigenetic changes following in-vitro culture is, however, unknown. This study was performed to evaluate the epigenetic (using whole-genome bisulfite sequencing (WGBS) and assay for transposase-accessible chromatin using sequencing (ATAC-seq)) and transcriptomic changes (using RNA-seq) occurring in the inner cell mass (ICM) of male or female mouse embryos generated in vivo or by IVF....
dc.source.conference


This item appears in the following Collection(s)

  • SDZWA Research Publications
    Peer reviewed and scientific works by San Diego Zoo Wildlife Alliance staff. Includes books, book sections, articles and conference publications and presentations.

Show simple item record